Phone: (412) 383-8011
Fax: (412) 383-6799
Email: kimsg@pitt.edu

Ph.D., Washington University

Research Interests

• Development of novel MR techniques to measure physiological changes induced by neural activity.
• Investigation of biophysics of MRI signals.
• Neurovascular and neurometabolic coupling.
• Exploration of the limits of spatial and temporal resolution of functional MRI (fMRI).
• Application of MR techniques to brain research.

Recent Publications

• Tanaka S, Moon CH, Fukuda M, Kim SG, “Three-dimensional visual feature representation in the primary visual cortex”, Neural Networks, 24: 1022-1035, 2011
• Yen CC, Fukuda M, Kim SG, “BOLD responses to different temporal frequency stimuli in the lateral geniculate nucleus and visual cortex: Insights into the neural basis of fMRI”, Neuroimage, Sep 1;58(1):82-90, 2011.
• Kim T & Kim SG. “Temporal dynamics and spatial specificity of arterial and venous blood volume changes during visual stimulation: implication for BOLD quantification”, J Cereb Blood Flow Metab. May;31(5):1211-22, 2011
• Swisher JD, Gatenby JC, Gore JC, Wolfe BA, Moon CH, Kim S-G, and Tong F, “Multiscale pattern analysis of orientation-selective activity in the primary visual cortex”, J of Neuroscience, 30(1):325-30, 2010.
• Vazquez A, Fukuda M, Tasker ML, Masamoto K & Kim SG. “Changes in Cerebral Arterial, Tissue and Venous Oxygenation with Evoked Neural Stimulation: Implications for Hemoglobin-based Functional Neuroimaging”, Journal of Cerebral Blood Flow and Metabolism, 30(2):428-39, 2010.
• Masamoto K, Fukuda M, Vazquez A, & Kim SG., “Dose-dependent effect of isoflurane on neurovascular coupling in rat somatosensory cortex”, European Journal of Neuroscience
, 30: 242-250, 2009
• Jin T & Kim S-G, “Cortical layer-dependent dynamic blood oxygenation, cerebral blood flow and cerebral blood volume responses during visual stimulation”, NeuroImage, 2008, 43(1):1-9.
• Moon C-H, Fukuda M, Park S-H, & Kim S-G, “Neural interpretation of blood oxygenation level-dependent fMRI maps at submillimeter columnar resolution”, J of Neuroscience. 2007 Jun 27;27(26):6892-902.
• Fukuda M, Moon C-H, Wang P, & Kim S-G, " Mapping iso-orientation columns by contrast agent-enhanced functional magnetic resonance imaging: reproducibility, specificity and evaluation by optical imaging of intrinsic signal", J of Neuroscience, 26(46):11821–11832, 2006.
• Duong TQ, Yacoub E, Adriany G, Hu X, Ugurbil K, Kim S-G: Microvascular BOLD contribution at 4 and 7T in the human brain: Gradient-echo and spin-echo fMRI with suppression of blood effects. Magn Reson Med 49: 1019-1027, 2003.
• Kim S-G, Ogawa S: Insights into new techniques for high resolution functional MRI. Curr Op Neurobiol 12: 607-15, 2002.
• Barbier EL, Silva AC, Kim S-G, Koretsky AP: Perfusion imaging using dynamic arterial spin labeling (DASL). Magn Reson Med 45: 1021-1029, 2001.

• Choi, I-Y, Lee S-P, Kim S-G, Gruetter R. In vivo measurements of brain glucose transport using reversible michaelis-menten model and simultaneous measurements of cerebral blood flow changes dring hypoglycemia. J Cereb Blood Flow & Metab 21: 653-663, 2001.

• Dassonville P, Lewis SM, Zhu X-H, Ugurbil K, Kim S-G, Ashe J: The effect of stimulus-response compatibility on cortical motor activation. Neuroimage 13(1): 1-14, 2001.

• Duong TQ, Iadecola C, Kim S-G: Effect of hyperoxia, hypercapnia and hypoxia on cerebral interstitial oxygen tension and cerebral blood flow. Magn Reson Med 45: 61-70, 2001.

• Duong TQ, Kim D-S, Ugurbil K, Kim S-G: Localized cerebral blood flow response at submillimeter columnar resolution. Proc Natl Acad Sci USA 98: 10904-10909, 2001.

• Ito H, Takahashi K, Hatazawa J, Kim S-G, Kanno I: Changes in human regional cerebral blood flow and cerebral blod volume during visual stimulation measured by positron emission tomography. J Cereb Flow & Metab 21: 608-612, 2001.

• Lee S-P, Duong TQ, Yang G, Iadecola C, Kim S-G: Relative changes of cerebral arterial and venous blood volumes during increased cerebral blood flow: Implications for BOLD fMRI. Magn Reson Med 45: 791-800, 2001.
• Ronen I, Kim S-G: Measurement of intravascular sodium during increased CBF using 23Na NMR with a shift agent. NMR in Biomedicine 14: 448-452, 2001.