Papers for the month of January 2017


"Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions"
Philosophical Transactions of the Royal Society Series B, 372:20160158

Mouse over here for a brief summary or click to open article in a new tab.Review of recent advances in the combined fields of homeostasis and Hebbian plasticity.


Tolin, D. F., Assaf, M., Goethe, J., Diefenbach, G. D.

"Cognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity"
Cognitive Therapy and Research, online first:online first

Mouse over here for a brief summary or click to open article in a new tab.We demonstrate that generalized anxiety disorder is characterized by deficits in the inhibition facet of executive functioning. Among patients with generalized anxiety disorder, the severity of inhibition deficits is positively associated with the severity of anxiety symptoms.


van den Bos W., Roeber B.J., Rudolph K.D., Davidson R.J., & Pollak S.D.

"Early adversity and learning: implications for typical and atypical behavioral development"
Journal of Child Psychology and Psychiatry, N/A:N/A

Mouse over here for a brief summary or click to open article in a new tab.In this work, we found that children and adolescents who suffered adversity had lower levels of reward learning overall and over the course of an experiment. We also found that this lower learning began to explain the higher levels of behavioral problems among youth who suffered early adversity.


Leathers, Marvin

"In Monkeys Making Value-Based Decisions Amygdala Neurons Are Sensitive to Cue Value as Distinct from Cue Salience."
Journal of Neurophysiology, Epub ahead of print:Not available

Mouse over here for a brief summary or click to open article in a new tab.hIn monkeys choosing between cues that predict rewards and penalties of variable size, amygdala neurons encode cue value whereas parietal neurons encode cue salience.


"Amygdala-prefrontal cortical functional connectivity during implicit emotion processing differentiates youth with bipolar spectrum from youth with externalizing disorders"
Journal of Affective Disorders, 208:94–100

Mouse over here for a brief summary or click to open article in a new tab.Amygdala functional connectivity in response to emotion processing is abnormal in youth with BPSD.


Lane S, Gates K, Kraynak TE, Horner MS, Thase ME, Siegle GJ

"Parsing heterogeneity in the brain connectivity of depressed and healthy adults during positive mood"
Biological Psychiatry, 81:347-357

Mouse over here for a brief summary or click to open article in a new tab.A data-driven clustering approach was used to identify subgroups based strictly on directed neural connectivity paths present during an fMRI positive mood task. The data-driven subgroups tracked with diagnostic status (depressed vs. healthy) as well as with a range of external variables assessing affective information processing and symptomatology.


Weinberg ZY, Zajac AS, Phan T, Shiwarski DJ

"Sequence-specific regulation of endocytic lifetimes modulates arrestin-mediated signaling at the μ opioid receptor"
Molecular Pharmacology, 91:3

Mouse over here for a brief summary or click to open article in a new tab.The mu opioid receptor is an essential target of clinically-relevant analgesic like morphine and drugs of abuse like heroin. This paper shows that the rate at which the receptor internalizes following drug addition controls the degree of signaling through one specific downstream pathway, while not affecting other signaling from the receptor.

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